Budenofalk对哮喘有多大效果？

It is a new type of inhaled glucocorticoid asthma treatment drug, which belongs to the adrenocortical hormone drugs. Budenofalk is approved for chronic reversible airway obstructive diseases such as bronchial asthma. How effective is Budenofalk for asthma?

The trial explores and analyzes the clinical effect of Budenofalk in the treatment of bronchial asthma. Methods: 92 patients with bronchial asthma admitted to our hospital from February 2013 to February 2015 were selected as the research subjects, and they were randomly divided into group A (46 cases) and group B (46 cases). Patients in group A were given conventional treatment, and patients in group B were treated with Budenofalk on the basis of conventional treatment. The clinical efficacy of the two groups of patients was then observed and compared, and the comparative results and clinical data of the two groups of patients were retrospectively analyzed.

Results: The clinical efficacy of patients in group B was significantly better than that of patients in group A, and the incidence of adverse reactions in patients in group B was significantly lower than that of patients in group A. The difference was significant (P<0.05) and was statistically significant. Conclusion: Budenofalk has significant clinical effect in treating bronchial asthma with few adverse reactions, and is worthy of clinical promotion and application.

It has a strong local anti-inflammatory effect, and its mechanism may be: enhancing the stability of mast cells and lysosomal membranes, reducing degranulation and the release of lysosomal enzymes; anti-immune effects, inhibiting inflammation caused by immune responses, etc.; for patients with airway hyperresponsiveness, Budenofalk can significantly reduce the airway response to histamine and methacholine. After inhalation, Budenofalk mainly inhibits the production of active substances such as inflammatory sensitization mediators and cytokines in the airways and lung tissues through the comprehensive effects of the above links, shrinks the expanded mucosal blood vessels, and increases the sensitivity of bronchial smooth muscle and inflammatory cells to β2 agonists. It can have a good therapeutic effect on both exogenous and endogenous asthma.