布地奈德疗效怎样？

(Budesonide, Budenofalk) How effective is it? Budesonide (Budenofalk) is a very effective drug for treating asthma. Let’s take a look at its clinical experimental research. Budesonide (Budenofalk) is a glucocorticoid with highly effective local anti-inflammatory effects. It can enhance the stability of endothelial cells, smooth muscle cells and lysosomal membranes, inhibit immune responses and reduce antibody synthesis, thereby reducing the release and activity of allergic active mediators such as histamine. It can also reduce the enzymatic process triggered when antigens and antibodies are combined, inhibit the synthesis and release of bronchoconstrictive substances and reduce the contractile response of smooth muscles. Acute, subacute and long-term toxicity studies have found that the systemic effects of budesonide, such as weight loss, lymphoid tissue and adrenal cortex atrophy, are weaker than or equivalent to other glucocorticoids. After systematic evaluation through six different experimental tests, Budesonide (Budenofalk) has no mutagenic or carcinogenic effects. 

85 patients with bronchial asthma who received treatment were selected and divided into an experimental group of 43 cases and a control group of 42 cases using the random number table method. Patients in the control group were treated with albuterol sulfate, and patients in the experimental group were treated with Budesonide (Budenofalk). After 2 weeks, the treatment effects and incidence of adverse reactions were compared. Results The treatment effectiveness rate of patients in the experimental group was 95.35%, which was significantly higher than the 69.05% in the control group, and the difference was statistically significant (P<0.05). No serious adverse reactions occurred in the two groups of patients, and the incidence of adverse reactions in the experimental group was significantly lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion (Budesonide, Budenofalk) has significant efficacy and high safety when applied to bronchial asthma. It is a good choice for patients.