布地奈德的用法和用量

(Budesonide) is a glucocorticoid with highly effective local anti-inflammatory effects. It can enhance the stability of endothelial cells, smooth muscle cells and lysosomal membranes, inhibit immune responses and reduce antibody synthesis, thereby reducing the release and activity of allergic active mediators such as histamine. It can also reduce the enzymatic process triggered when antigens and antibodies are combined, inhibit the synthesis and release of bronchoconstrictive substances and reduce the contractile response of smooth muscles.

The dose of Budesonide nasal spray should be individualized for rhinitis: the recommended starting dose for adults and children over 6 years old is 256ug per day. This dose can be sprayed once in the morning or twice in the morning and evening. That is: spray 128ug (2*64ug) into each nostril in the morning; or spray 64ug into each nostril twice in the morning and evening. No increase in effect was seen when the daily dose exceeded 256ug. After the desired clinical effect is achieved, reduce dosage to the low doses needed to control symptoms. Clinical trials have shown that some patients spraying 32ug into each nostril every morning as a maintenance dose is sufficient. Some patients experience relief of symptoms 5-7 hours after starting treatment. Full effects may be achieved after several days of treatment (2 weeks in a few patients). Therefore, treatment of seasonal rhinitis is best initiated before allergen exposure, if possible. Severe nasal congestion may require the use of vasoconstrictor drugs. Adjuvant treatments may sometimes be needed to control eye symptoms caused by allergies.

Treatment or prevention of nasal polyps: The recommended dose of Budesonide is 256ug per day. This dose can be sprayed once in the morning or twice in the morning and evening. After obtaining the desired effect, reduce the dosage to the minimum dose that controls symptoms as a maintenance dose. For adults aged 18 and over to treat allergic rhinitis, a 32ug spray is available without a prescription and can be used for up to 3 months.

The above is the usage and dosage of Budesonide provided by our Medical Travel Overseas Medical Consulting Service Company. Patients must read the instructions carefully and use Budesonide with caution.