Side effects and precautions of Effluprofen patch

Efluprofen patch is a new transdermal absorption non-steroidal anti-inflammatory analgesic patch, mainly used to treat local pain and inflammation caused by osteoarthritis. The drug exerts anti-inflammatory and analgesic effects by potently inhibiting COX-1 and COX-2, and has the characteristics of strong local effect and low systemic exposure. Patients should understand its side effects, usage precautions and clinical efficacy before taking the medication.

Side effects of Efloprofen Patch

Efloprofen Patch may cause a variety of adverse reactions during use, ranging from mild local irritation to severe systemic reactions. Understanding these side effects will help to take timely countermeasures.

Common local reactions

Dermatitis at the application site is the most common side effect, manifesting as erythema, itching, eczema or rash. Some patients may experience pigmentation or irritation. These reactions are usually mild and resolve spontaneously after stopping the drug.

Systemic adverse reactions

Long-term use may cause central nervous system symptoms such as headaches and dizziness, as well as gastrointestinal discomforts such as gastritis and abdominal pain. Clinical examination shows that serum urea, creatinine and other indicators are increased, and relevant indicators need to be monitored regularly.

Serious adverse reactions

Although rare, serious reactions such as anaphylactic shock and acute kidney injury may be life-threatening. If symptoms such as difficulty breathing, severe rash, or impaired consciousness occur, you should stop taking the medicine immediately and seek medical advice.

Effluprofen patch has a wide spectrum of side effects, ranging from local skin reactions to systemic reactions. Patients need to be closely monitored under the guidance of a doctor.

Precautions for Efloprofen Patch

Special attention should be paid to the following matters when using Efloprofen Patch to avoid unnecessary risks.

Selection of application site

Do not apply on damaged, eczema or rash areas. Every time you change the application site, gently clean your skin with warm water and allow it to air dry naturally to avoid irritation.

Drug interactions

Combined use with quinolone antibiotics may induce spasm, and combined use with warfarin can enhance the anticoagulant effect. Inform your doctor of all medications you are taking before use to avoid adverse interactions.

Usage for special groups

It is contraindicated for pregnant women in the third trimester of pregnancy, and the elderly should use it in reduced doses. Patients with hepatic and renal insufficiency need to adjust the dosage and strengthen monitoring. The safety in children has not been established and its use is not recommended.

Strictly complying with the precautions for the use of Efluprofen patches is an important guarantee for preventing adverse reactions and ensuring therapeutic effects.

Effectiveness of Efloprofen Patch

Efloprofen Patch has shown significant efficacy in the treatment of osteoarthritis-related pain, and its unique mechanism of action brings multiple therapeutic advantages.

Quick onset of action

After percutaneous absorption, the drug can directly act on the painful area and take effect quickly. Clinical observation shows that most patients can feel pain relief within 1-2 hours after application.

Strong local effect

Pharmacokinetic studies show that the drug concentration in the synovium and synovial fluid after application is significantly higher than the plasma concentration. This targeted distribution ensures a strong local anti-inflammatory and analgesic effect.

Low systemic exposure

Compared with oral preparations, transdermal administration greatly reduces systemic drug exposure and reduces the risk of systemic adverse reactions such as gastrointestinal tract.

With its rapid onset of action, potent local action, and low systemic exposure, the efluprofen patch provides an effective treatment option for patients with osteoarthritis.