狄诺塞麦哪里有售？

Subcutaneous injection of 120 mg into the upper arm, upper thigh, or abdomen once every 4 weeks is used to treat patients with bone metastases from solid tumors and prevent bone-related events. When treatment or prevention of hypocalcemia is required, calcium and vitamin D are given.

Denosumab is the first approved monoclonal antibody specifically targeting RANK ligand. RANK ligand is a transmembrane or soluble protein that is necessary for osteoclasts to maintain their structure, function, and survival. Human RANKL mRNA is mainly found in bones, bone marrow and lymphoid tissues. Its main function in bones is to stimulate the differentiation and activity of osteoclasts and inhibit the apoptosis of osteoclasts.

The latest analysis of research presented at the European Society for Medical Oncology (ESMO) Annual Meeting in 2017 showed that among patients who could be surgically resected, 80% improved after receiving neoadjuvant denosumab: 44% underwent surgery with less impact on function, and 37% avoided surgery. In unresectable patients, denosumab resulted in effective long-term disease control, with a 5-year progression-free survival (PFS) rate of 88%.

Where can I buy Denosumab? Denosumab entered the Chinese market in May 2019. However, because it was conditionally approved for marketing, not all domestic patients with bone metastases can easily buy denosumab. In comparison, patients are better off buying Turkish denosumab.

Medical Companion Brigade learned that Turkish denosumab is also produced by Amgen, but its pricing in Turkey is relatively low, which can greatly reduce patients’ medication burden. The specification of Turkish denosumab is 125mg/1ml tube/box, and the price is equivalent to RMB 3,000.

Patients who are convenient to go abroad can go abroad to purchase Türkiye by themselves, and patients who are inconvenient to go abroad can contact domestic professional overseas medical institutions to purchase.