地舒单抗一盒多少钱呢？

The US FDA approved it to prevent skeletal-related events (SREs) in tumor patients whose cancer has metastasized and damaged bone; so-called skeletal-related events include fractures and pain caused by cancer. Important limitations of use: Not indicated for the prevention of bone-related events in patients with multiple myeloma.

So, how much does a box of denosumab cost?

Price of denosumab: Many patients are very concerned about the price of denosumab in China. Since denosumab is conditionally approved for marketing in China and has not been fully popularized, the domestic price of denosumab is not very clear!

According to Medical Companion Travel, the price of denosumab 120mg produced by Amgen in the United States is about $3,000. Due to the floating exchange rate, the price will be different. Please consult Medical Companion Travel for specific prices!

Desosumab Warnings and Precautions:

(1) Hypocalcemia, severe hypocalcemia, may occur in patients receiving denosumab. Correct hypocalcemia before initiating denosumab. Monitor calcium levels and appropriately supplement all patients with calcium and vitamin D.

(2) Osteonecrosis of the jaw may occur in patients receiving denosumab. Perform an oral examination before starting denosumab. Monitor for symptoms. Avoid invasive dental procedures during treatment with denosumab.

Desosumab usage and dosage:

Give 120 mg by subcutaneous injection into the upper arm, upper thigh, or abdomen once every 4 weeks. 

120 mg/1.7 mL (70 mg/mL) single use vial.

Desosumab is used in special populations:

(1) Pregnancy: According to animal data, it may cause fetal damage. Pregnancy monitoring programs are available.

(2) Nursing mothers: Mammary gland development and lactation may be impaired. Discontinue medication or breastfeeding.

(3) Pediatric patients: Solace and effectiveness have not been determined.

(4) Renal impairment: Patients with creatinine clearance less than 30 mL/min or receiving dialysis are at risk for hypocalcemia. Appropriate supplement of calcium and vitamin D during use.