狄诺塞麦怎么打？

The treatment for bone metastases (denosumab) has been well received since its launch. However, many patients don’t know how to take denosumab (denosumab) when they buy it home. The editor will give you a brief introduction below:

(1) Denosumab (denosumab) can only be injected subcutaneously, not intravenously, intramuscularly or intradermally.

(2) Solid tumor bone metastasis: 120mg once every 4 weeks, injected subcutaneously in the upper arm, thigh or abdomen.

(3) Giant cell tumor of bone: 120 mg once every 4 weeks, subcutaneous injection, and another 120 mg on day 8 and day 15 in the first month of treatment.

(4) Administer calcium and vitamin D appropriately to prevent hypocalcemia.

(5) Malignant hypercalcemia: 120 mg once every 4 weeks, subcutaneous injection, and another 120 mg on day 8 and day 15 in the first month of treatment. The medication is injected under the skin in the upper arm, thigh, or abdomen.

Denosumab (denosumab) adverse drug reactions:

The most common adverse reactions in patients with bone metastases from solid tumors include: weakness/fatigue, nausea, and hypophosphatemia.

Common adverse reactions in patients with giant cell tumor of bone include joint pain, headache, back pain, nausea, limb pain, and fatigue.

Precautions when taking denosumab (denosumab):

1. Osteonecrosis of the jaw may occur in patients receiving denosumab (denosumab). Perform an oral examination before starting denosumab, monitor symptoms, and avoid invasive dental procedures during treatment.

2. Patients receiving denosumab (denosumab) may develop hypocalcemia and severe hypocalcemia. Calcemia should be corrected before starting medication, and calcium levels should be monitored and all patients appropriately supplemented with calcium and vitamin D.

When injecting (denosumab), patients must refer to the doctor's instructions and instructions, and complete the injection under the operation of medical staff.

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