美国安进狄诺塞麦多久打一次？

(Denosumab) is a human RANKL monoclonal antibody (IgG2) with high affinity and specificity. It can bind to and act on RANKL to inhibit bone tissue destruction by osteoclasts, providing rapid and sustained bone turnover inhibition for patients with multiple myeloma, osteolytic bone disease, breast cancer bone metastasis, and prostate cancer bone metastasis; inhibition of RANK/RANKL may also kill osteoclast-like giant cells and related monocytes in giant cell tumors of bone. So, how often should Amgen take denosumab in the United States?

Denosumab is easy to use and can be injected subcutaneously by the patient at 60 mg/time with an interval of 6 months. While being treated with this drug, patients need to take 1000mg of calcium and at least 4001U of vitamin D every day. It is worth noting that unlike bisphosphonates, which maintain their effects for a long time, denosumab does not bind to its receptors for long-term storage. There are reports that denosumab has a reversible effect on increasing bone density and improving bone turnover indicators. When drug use is interrupted (longer than the treatment interval), rapid bone loss will bring about the risk of multiple vertebral fractures.

According to Medical Travel, a box of denosumab produced by Amgen in the United States is only about $1,500, which is a decrease compared to the same period last year as the price of original drugs sold in China. Patients in need can, on the one hand, go abroad in person to purchase drugs locally, and on the other hand, they can also contact Medical Companion Travel to obtain their overseas drug purchase channels. Patients can also have more peace of mind and peace of mind.

Amgen Biopharmaceutical Company (Amgen) is the world's leading innovative biopharmaceutical R&D and manufacturing company. It takes "drug innovation" as its core concept and attaches great importance to the accumulation of R&D capabilities. It has achieved major breakthroughs in the fields of human genome, tumor biology, neuroscience, hematology and other fields. As one of Amgen's important products, it is trustworthy.

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