美国安进地舒单抗注射液的使用说明

The original drug of Xgeva was developed by Amgen in the United States and is currently approved for multiple indications around the world. Amgen Biopharmaceutical Company (Amgen) is the world's leading innovative biopharmaceutical R&D and manufacturing company. It takes "drug innovation" as its core concept and attaches great importance to the accumulation of R&D capabilities. It has achieved major breakthroughs in the fields of human genome, tumor biology, neuroscience, hematology and other fields.

The mechanism of action of denosumab Xgeva: denosumab Xgeva binds to RANKL, a transmembrane or soluble protein that plays an important role in the formation, function, survival of osteoclasts and cells responsible for bone resorption, and regulates the release of calcium from bone.

Instructions for use of Amgen's denosumab injection in the United States: Desomasumab Xgeva is simple and easy to use. Patients can subcutaneously inject 60 mg/time by themselves, with a 6-month interval between doses. While being treated with denosumab Xgeva, patients need to take 1000mg of calcium and at least 4001U of vitamin D per day. Patients should not increase or decrease the dose of the drug without authorization while receiving denosumab Xgeva. Increasing the dose of denosumab will not make the condition improve quickly, but will lead to adverse reactions. Only correct use of the drug will help the condition. Therefore, patients should strictly follow the doctor's instructions.

It is worth noting that unlike bisphosphonates, which maintain long-term effects, denosumab Xgeva does not bind to its receptors for long-term retention. Reports have shown that the effect of denosumab Xgeva on increasing bone density and improving bone turnover indicators is reversible. When drug use is discontinued, acute bone loss will bring about the risk of multiple vertebral fractures. Patients should be aware of this.

The above is the introduction to Xgeva. If patients have other questions about denosumab Xgeva (such as drug prices, purchase channels, etc.), they can consult the medical companion travel service.

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