美国安进地舒单抗注射液的价格
Xgeva injection is a human immunoglobulin G2 (IgG2) monoclonal antibody with high specificity and affinity for RANKL. Desosumab Xgeva blocks the activation of the RANK signaling pathway of osteoclasts by binding to RANKL, breaking the "vicious cycle" of cancer bone metastasis, thereby achieving the purpose of inhibiting tumor growth and reducing bone destruction.
Desosumab Xgeva was approved by the National Medical Products Administration (NMPA) in May 2019 for the treatment of giant cell tumor of bone (GCTB) that is unresectable or whose surgical resection may cause severe dysfunction, including adults and skeletally mature adolescent patients.
It is worth noting that unlike bisphosphonates, which maintain long-term effects, denosumab Xgeva does not bind to its receptors for long-term retention. Reports have shown that the effect of denosumab Xgeva on increasing bone density and improving bone turnover indicators is reversible. When drug use is discontinued, acute bone loss will bring about the risk of multiple vertebral fractures. Patients should be aware of this.
The original drug of denosumab Xgeva was developed by Amgen of the United States. Amgen Biopharmaceutical Company (Amgen) is the world's leading innovative biopharmaceutical R&D and manufacturing company. It takes "drug innovation" as its core concept and attaches great importance to the accumulation of R&D capabilities. It has achieved major breakthroughs in the fields of human genome, tumor biology, neuroscience, hematology and other fields. Price of Amgen denosumab injection in the United States:
Desosumab Xgeva produced by Amgen Biopharmaceuticals in the United States is exported to China. Specification: 120mg/1.7ml bottle/box. Pharmacy price: RMB 5,298.00. Desosumab Xgeva produced by Amgen Biopharmaceuticals in the United States has the specifications in the United States: 60mg/1ml tube/box, price: US$1,169.98.
Xgeva produced by Amgen Biopharmaceuticals in the United States is exported to Turkey in the form of 120 mg and sells for about $1,500. Since the exchange rate floating price is not fixed, if patients want to know the specific price information of denosumab Xgeva, they can consult the medical companion travel service.
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