武田千寿滴耳液的适应症

Takeda Senju Ear Drops is an antibacterial preparation containing tobramycin, which has important application value in the field of treatment of eye and ear infections. This article will systematically introduce the scope of indications, pharmacological effects and contraindications of this drug to help medical professionals and patients fully understand its clinical characteristics.

Indications of Takeda Senju Ear Drops

Takeda Senju Ear Drops have a clear scope of clinical application, mainly targeting specific types of eye and ear infections.

Ophthalmic indications

It is suitable for the treatment of eye infections such as bacterial conjunctivitis and keratitis. In the perioperative period, it can be used for aseptic prophylaxis before eye surgery. Eye drops should be administered 5 times a day starting 2 days before surgery.

Otological indications

For bacterial ear infections such as otitis externa and otitis media. After each 6-10 drops of ear drops, the ear bath should be maintained for about 10 minutes, twice a day.

Treatment course control requirements

It is recommended that the treatment cycle should not exceed 4 weeks. Long-term use may lead to bacterial imbalance or the development of drug resistance. After symptoms are relieved, the prescribed course of treatment must still be completed.

The indications of Takeda Senju Ear Drops are clearly focused on bacterial eye and ear infections, and standardized use can effectively control the symptoms of infection.

Efficacy and role of Takeda Senju Ear Drops

This drug exerts antibacterial therapeutic effects through its unique pharmacological mechanism.

Principle of antibacterial action

The main component tobramycin interferes with protein synthesis by irreversibly binding to the bacterial 30S ribosome subunit, and is effective against a variety of Gram-negative bacteria and some Gram-positive bacteria.

Local drug concentration

The drug concentration in the aqueous humor can reach 2.69μg/mL 90 minutes after eye drops. The drug concentration in the middle ear mucosa reaches its peak 1-2 hours after otology use, and the therapeutic concentration can be effectively achieved.

Clinical efficacy characteristics

It has rapid onset of action, high local drug concentration and low systemic absorption. The blood drug concentration is lower than the lower limit of detection, reducing the risk of systemic side effects.

Takeda Senju Ear Drops treat infections with potent local antimicrobial action while minimizing systemic effects.

Contraindications of Takeda Senju Ear Drops

It is necessary to avoid using this drug under certain circumstances, and the contraindications should be understood under the guidance of a doctor.

Absolute contraindications

It is prohibited for those allergic to tobramycin or any ingredients in the preparation. Those who have experienced severe allergic reactions such as difficulty breathing or decreased blood pressure in the past are prohibited from using it again.

Relative contraindications

Pregnant and lactating women need to carefully evaluate the risk-benefit ratio, and patients with severe renal insufficiency need to use it under the supervision of a doctor.

Restrictions for special groups

Safety data for use in infants under 6 months old are limited, and medical advice must be strictly followed. The elderly must consider their renal function when taking medication.

Understanding the contraindications of Takeda Senju Ear Drops is crucial for safe use. Special groups should consult a professional physician before use.