氯替泼诺混悬滴眼液(Lotemax)是治疗什么疾病的

Loteprednol Suspension Eye Drops (Lotemax) is a topical corticosteroid ophthalmic preparation mainly used to control eye inflammation and related symptoms.

What diseases does Loteprednol Suspension Eye Drops (Lotemax) treat?

Loteprednol Ebonate is a synthetic corticosteroid with an optimized chemical structure that has high local anti-inflammatory activity and a low risk of systemic side effects.

Supplied in the form of suspension eye drops, it is suitable for post-ophthalmic surgery management.

Indications of Loteprednol Suspension Eye Drops (Lotemax)

1. Indications

Steroid-reactive inflammation of the eyelids, bulbar conjunctiva, cornea and anterior segment of the eye (such as allergic conjunctivitis, rosacea, superficial punctate keratitis, herpetic keratitis, iritis, cyclitis, etc.); selective infectious conjunctivitis (after weighing the risks of steroid use); postoperative inflammation control.

2. Applicable population

It is suitable for adult patients. The safety and effectiveness of the drug for children have not yet been established.

The pictures come from public channels (such as the official website of the FDA, the official website of the original drug manufacturer, etc.) and are for reference only.

The efficacy of Loteprednol Suspension Eye Drops (Lotemax)

1. Postoperative inflammation

Placebo-controlled clinical studies have proven that Loteprednol Suspension Eye Drops can effectively treat anterior chamber inflammation, and its efficacy is measured by the reduction of anterior chamber cells and flares.

2. Giant papillary conjunctivitis

Based on multiple placebo-controlled clinical studies, it has been proven that Loteprednol Suspension Eye Drops can reduce the signs and symptoms of giant papillary conjunctivitis. The therapeutic effect can begin 1 week after treatment and last until the 6th week of treatment.

3. Seasonal allergic conjunctivitis

A placebo-controlled clinical study demonstrated that loteprednol suspension eye drops can effectively reduce the signs and symptoms of allergic conjunctivitis during the peak period of pollen exposure.

4. Uveitis

Controlled clinical studies on patients with uveitis have shown that the efficacy of loteprednol suspension eye drops is lower than 1% prednisolone acetate. Overall, the majority of patients using loteprednol suspension eye drops achieved anterior chamber cell regression by day 28 of treatment.

Contraindications of Loteprednol Suspension Eye Drops (Lotemax)

Loteprednol Suspension Eye Drops are contraindicated in most viral corneal and conjunctival diseases, including epithelial herpes simplex keratitis (dendritic keratitis), vaccine viral eye disease, chickenpox, and mycobacterial and fungal infections of the eye.

Patients should receive a comprehensive eye examination before use to rule out the above infections.