氯替泼诺混悬滴眼液(Lotemax)的副作用如何缓解

Loteprednol suspension eye drops (Lotemax) was developed by Bausch & Lomb of the United States. It is a glucocorticoid ophthalmic drug and was first approved for marketing in the United States in 1998.

Side effects of Loteprednol Suspension Eye Drops (Lotemax)

1. Ocular adverse reactions

In clinical studies, about 25% of patients reported anterior chamber inflammation. Other common adverse reactions include conjunctival hyperemia, corneal edema and eye pain, with an incidence rate of approximately 4%-5%.

2. Increased intraocular pressure

Long-term abuse of corticosteroids may not only increase intraocular pressure, but may even push glaucoma to a more serious stage, eventually causing irreversible damage to the optic nerve and visual field defects.

3. Cataract formation

Steroid use may also cause posterior subcapsular cataracts.

4. Delayed healing and risk of infection

Postoperative use of steroids may delay wound healing and increase the incidence of follicle formation.

In addition, bacterial, viral, or fungal infections may be masked or aggravated, so patients with a history of herpes simplex should be particularly cautious.

The pictures come from public channels (such as the official website of the FDA, the official website of the original drug manufacturer, etc.) and are for reference only.

Loteprednol Suspension Eye Drops (Lotemax) side effects relief

1. Monitoring and follow-up examination

If eye discomfort occurs, such as eye pain, redness and swelling, or uncontrollable itching, or even the original inflammation suddenly worsens, stop using the drug immediately and seek medical treatment in time. If used for more than 10 days, intraocular pressure should be checked regularly, and fundus and visual acuity should be evaluated if necessary.

2. Avoid extending the medication on your own

Patients should not increase the frequency of medication or abuse the medication on their own. Continued use after 14 days must be evaluated by a doctor and examined under a microscope and other equipment.

3. Pay attention to hygiene and protection

To avoid contamination caused by the mouth of the tube coming into contact with eyes or skin during operation, wash your hands before operation. Contact lenses should not be worn while taking this medication.

4. Symptomatic treatment

If mild discomfort occurs, artificial tears can be used to relieve dryness; if symptoms persist or worsen, seek medical treatment in time to rule out infection or other complications.

Correct usage of Loteprednol Suspension Eye Drops (Lotemax)

1. Dosing time and frequency

It is recommended to start using it 24 hours after surgery. Take about half an inch (1.3 cm) of ointment each time and apply it into the conjunctival sac four times a day for two weeks.

2. Usage steps

(1) Wash hands thoroughly before use.

(2). Look up, gently pull down the lower eyelid, and squeeze the ointment into the conjunctival sac.

(3) Close your eyes and gently press the inner corners of your eyes for 1 minute to promote drug absorption.

(4). Wipe off excess ointment with a clean paper towel and avoid contacting the nozzle with any surface.

3. Storage conditions

Store loteprednol suspension eye drops in an environment between 15°C and 25°C. After opening, it can be used before the expiry date. Please close the cap tightly and avoid high temperature and direct sunlight.

4. Medication for special groups

Especially for special groups such as pregnant women, lactating women, children and the elderly, the use must be under the guidance of a doctor. There is a lack of corresponding data to support the safety and effectiveness of use in this group of children.