盐酸缬更昔洛韦片多少钱一盒？

It is an oral anti-cytomegalovirus infection drug developed by the Swiss company Roche. Its main ingredient is valganciclovir hydrochloride. Valganciclovir is the L-valyl ester (prodrug) of ganciclovir, which is rapidly converted into ganciclovir by esterases in the small intestine and liver after oral administration. Ganciclovir is a synthetic 2'-deoxyguanosine analog that inhibits herpes virus replication in vitro and in vivo. Susceptible human viruses include human cytomegalovirus (HCMV), herpes simplex virus-1 and herpes simplex virus-2 (HSV-1, HSV-2), human herpesvirus-6, 7, 8 (HHV-6, 7, 8), Epstein-Barr virus, varicella-zoster virus (VZV), and hepatitis B virus.

In cells infected with cytomegalovirus (CMV), ganciclovir is first phosphorylated by the viral protein kinase UL97 to ganciclovir monophosphate. It is further phosphorylated by intracellular protein kinases into ganciclovir triphosphate, which is then slowly metabolized within the cell. After removal of extracellular ganciclovir, the observed half-life of ganciclovir in HSV- or HCMV-infected cells was 18 hours (6-24 hours), respectively. Since the phosphorylation process relies heavily on viral protein kinases, ganciclovir phosphorylation occurs preferentially in virus-infected cells.

How much does a box of Valganciclovir Hydrochloride Tablets cost?

Valganciclovir Hydrochloride Tablets are already on the market in China and are relatively expensive. Most patients say they cannot afford it. The domestic Valganciclovir Hydrochloride Tablets range from 450mg to 60 tablets per box and are priced at approximately RMB 16,500$.

Fortunately, Roche is also on the market in India, and the price is the lowest in the world. India's Valgancilovir (valganciclovir hydrochloride tablets, valgansiklovir) 450mg*60 tablets/box is priced at about RMB 5,500. Due to the floating exchange rate, the price is not fixed. Please consult Medical Travel for specific prices.