万赛维功效作用

The tablets are pink oval film-coated oral tablets. The main ingredient of Valganciclovir tablets is valganciclovir hydrochloride. So, what are the efficacy and functions of Vancevi tablets?

Efficacy: In May 2001, the US FDA approved the market. Valcyte tablets are clinically used to treat acute retinitis caused by CMV infection in patients with acquired immunodeficiency syndrome. In May 2003, its indications were expanded. Valcyte tablets are used to prevent and treat secondary CMV infection in organ transplant recipients. On August 11, 2010, Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), announced that the U.S. Food and Drug Administration (FDA) approved Valcyte for the treatment of adult kidney transplant patients at high risk for cytomegalovirus (CMV) disease. Roche announced on August 31, 2009 that the U.S. Food and Drug Administration (FDA) has approved Valcyte (trade name: Valcyte; generic name: valganciclovir hydrochloride) for the prevention of cytomegalovirus (CMV) infection in pediatric kidney and heart transplant patients aged 4 months to 16 years. Such children are considered to be a high-risk group for CMV infection.

Function: The tablet is the prodrug of ganciclovir. Vansevir tablets can be well absorbed from the gastrointestinal tract and rapidly metabolized into ganciclovir in the small intestinal wall and liver. The absolute bioavailability of ganciclovir converted from valganciclovir is approximately 60%. The systemic exposure of Vansevir tablets is small and transient, and the 24-hour area under the curve AUC24 and peak concentration (Cmax) are only 1% and 3% of ganciclovir respectively. The proportional relationship between the oral dose of valganciclovir hydrochloride tablets of 450-2625 mg and the AUC of ganciclovir was only studied under postprandial conditions. When Vancevir tablets at the recommended dose of 900 mg were taken with food, the mean AUC24 and Cmax of ganciclovir were increased by approximately 30% and approximately 14%, respectively. Therefore, it is recommended to take Vancevi tablets with food.