万赛维治疗CMV视网膜炎效果好吗?
, also known as Valganciclovir Hydrochloride Tablets, etc., is an antiviral drug used to treat patients with acquired immunodeficiency syndrome (AIDS) combined with cytomegalovirus (CMV) retinitis, and to prevent CMV infection in high-risk solid organ transplant patients. Vancevir needs to be taken long-term because it only suppresses the infection, not cures it. Vancevir is a prescription antiviral drug.
In adults, use Vancevir: To treat cytomegalovirus (CMV) retinitis in people with immunodeficiency syndrome (AIDS). When the CMV virus infects the eye, it is called CMV retinitis. If CMV retinitis is not treated, blindness may result. To prevent CMV disease in people who have received a kidney, heart, or kidney-pancreas transplant and are at high risk for CMV disease. Vansevir is the prodrug of ganciclovir and is rapidly converted into ganciclovir after oral administration.
So, what is the efficacy of Vancevi in treating CMV retinitis? Let's take a look.
Clinical studies of valganciclovir tablets in AIDS patients infected with CMV retinitis have shown that valganciclovir hydrochloride tablets and intravenous ganciclovir are equally effective in the induction treatment of CMV retinitis. In the study, patients with newly diagnosed CMV retinitis were randomly assigned to the vancevir group or the intravenous ganciclovir group for induction therapy. The proportion of patients with progression of CMV retinitis at week four was the same in both groups. After induction therapy, both groups of patients in the study continued to receive maintenance therapy with Vancevir tablets 900 mg per day. The mean (median) time from randomization to progression of CMV retinitis was 226 (160) days and 219 (125) days in patients who received Vancevir tablets or intravenous ganciclovir induction therapy followed by Vancevir tablets as maintenance therapy, respectively.
From this point of view, the efficacy of Vancevi in treating CMV retinitis is relatively ideal. Patients must strictly follow the doctor's instructions and take the medication on time, so that the efficacy of the drug can be maximized.
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