The latest price of larotrectinib in 2024 published on the entire network

Introduction: Larotrectinib is a highly selective, ATP-competitive tyrosine kinase inhibitor (TKI) that can inhibit three isoforms of the TRK family (TrkA, TrkB and TrkC) and is used to treat tumors with TRK fusion characteristics in different tissues or cells.

The latest price of larotrectinib in 2024 announced on the entire website

has been launched in China and has been included in medical insurance. The winning price of larotrectinib sulfate capsules in medical insurance is 31,500$, and larotrectinib sulfate oral solution The winning bid prices for medical insurance are 5,625$ and 11,250$. The price after medical insurance reimbursement will be cheaper, and the specific price needs to be calculated according to the reimbursement ratio in each region.

In addition, there are also generic versions of larotrectinib. Among them, larotinib produced by Lucius in Laos is 100mg*30 capsules/box, and the price of a box is about 1500$-2000$. Larotinib produced by Everest in Bangladesh is 100mg*30 capsules/box, and the price of a box is about 4000$-4500$.

is for reference only. The actual price at the time of purchase may change due to factors such as drug version, medical insurance reimbursement policy, purchase channel, etc. Patients are advised to refer to the actual price at the time of purchase.

Drug interactions with larotrectinib

Avoid coadministration of larotrectinib with strong CYP3A4 inhibitors (including grapefruit or grapefruit juice), strong CYP3A4 inducers, or sensitive CYP3A4 substrates. If coadministration of strong CYP3A4 inhibitors or inducers cannot be avoided, adjust the larotrectinib dose as recommended. If coadministration of sensitive CYP3A4 substrates cannot be avoided, monitor patients for an increase in adverse reactions from these drugs.

For coadministration with moderate CYP3A4 inhibitors, monitor for adverse reactions more frequently and reduce dose based on severity, and for coadministration with moderate CYP3A4 inducers, adjust dose as recommended.

How to store larotrectinib

1. Storage temperature: Larotrectinib capsule dosage form should be stored at room temperature, that is, within the temperature range of 15°C-30°C (59°F-86°F).

2. Packaging and storage: Drugs are usually provided in sealed bottles. Keep medication bottles sealed and make sure the cap is properly closed after each use to protect medications from outside air, moisture, or other contaminants.

3. Avoid exposure to light: Larotrectinib should be avoided from prolonged exposure to strong light or direct sunlight. Medication bottles should be stored out of direct light, such as in a cabinet or in an opaque medication container.

Please be sure to follow these storage conditions to maintain larotrectinib potency and stability. If in any doubt, it is recommended to consult a professional physician or pharmacist.