Latest prices for a box of different versions of larotrectinib announced

Introduction: Larotrectinib is an anti-cancer drug for the treatment of solid tumors with NTRK gene fusion. NTRK gene fusion is a rare genetic abnormality that may occur in tumors in different parts of the body, such as the lungs, thyroid and intestines. Larotrectinib is used to treat patients whose tumors are advanced, have spread to other parts of the body, or are not candidates for surgery and who have no satisfactory alternative treatments.

The latest prices for a box of different versions of larotrectinib are announced

The prices of different versions of larotrectinib are also different. The more common versions and prices are as follows.

1. Original drug version: produced by Bayer AG (Germany) has been launched in China. The winning price of medical insurance is 31,500$ per box. The price after medical insurance reimbursement will be cheaper. For the specific price after reimbursement, you need to consult the local medical insurance department or hospital.

2. Generic drug versions: The price of Laotian Lucius’s generic larotrectinib is about 1500$-2000$ per box, and the price of Bangladesh Everest’s generic larotrectinib is about 4000$-4600$ per box.

The above prices are for reference only. may be affected by various factors, and patients should refer to the actual selling price. When taking larotrectinib, you must follow the doctor's instructions carefully, understand the medication instructions of larotrectinib, and do not self-medicate.

How to take larotrectinib

Larotrectinib is available in liquid (20 mg per ml) and capsule (25 mg and 100 mg) forms. Adult patients whose cancer is stable and side effects are acceptable should take 100 mg twice daily. The dose for children is based on their body surface area (weight and height). The recommended dose for pediatric patients is 100 mg/m² twice daily until disease progression or unacceptable toxicity occurs. If adverse events occur, the dose should be gradually reduced by 25 mg increments based on patient tolerance.

Larotrectinib should be started by a doctor experienced in using anti-cancer drugs and can only be purchased with a prescription. For more information about the use of larotrectinib, it is recommended to consult the package insert or contact your doctor.

What are the risks of larotrectinib

The most common side effects of larotrectinib (which may affect more than one in five people) are fatigue, dizziness, constipation, nausea, vomiting, anemia, and elevated levels of alanine aminotransferase and aspartate aminotransferase in the blood.

Most of the side effects of larotrectinib are mild to moderate and do not require special treatment. However, if the side effects are severe or last for a long time, it is recommended to inform the doctor in time, and the doctor will carry out targeted treatment.