呲仑帕奈说明书

Instructions

Common name: perampanel

Product name: Fycompa

All names: perampanel, victoria, Fycompa, perampanel

Indications: Parampanel is indicated for the add-on treatment of partial-onset epilepsy (with or without secondary generalized seizures) in adults and children 12 years and older.

Usage and Dosage: Perampanel can be taken once a day before going to bed, on an empty stomach or with food. Perampanel should be swallowed whole and should not be chewed, crushed, or broken. Since there are no marks on the medicine, this product cannot be opened evenly.

Taboo:

It is contraindicated in those allergic to the active ingredient of parampanel or lactose. Because parampanel contains lactose, patients with rare hereditary galactose intolerance, Lapp lactase deficiency, or glucose-galactose intractable disease should not use it.

Things to note:

1. Suicidal ideation

2. Various neurological diseases

3. Oral contraceptives

4. fall

5.Attack

6. Other symptoms of mental illness

7.Social environment

8. Potential for abuse

Adverse reactions: The main adverse reactions of parampanel include: dizziness, drowsiness, headache, fatigue, irritability, nausea, and falls

Mechanism of action: Perampanel, the active substance in perampanel, is an anti-epileptic drug. Epilepsy is caused by excessive electrical activity in the brain. While the exact mechanism by which valampanel works is not fully understood, it is thought to block the effects of the neurotransmitter glutamate. Neurotransmitters are naturally occurring chemicals in the nervous system that allow nerve cells to communicate with each other. Glutamate is the primary stimulatory neurotransmitter in nerve cells that can initiate and sustain epileptic seizures. Therefore, by blocking the effects of glutamate, garampanel is thought to prevent seizures.

Safety and Efficacy: The efficacy of perampanel, a partial-onset seizure treatment drug, was established in three 19-week randomized, double-blind, placebo-controlled, multicenter add-on treatment trials in adults and adolescents. Subjects had partial seizures with or without secondary generalized seizures that were not adequately controlled while receiving 1 to 3 concomitant AEDs. During the 6-week baseline period, subjects had more than 5 seizures and no more than 25 days of epilepsy-free seizures. Across the three trials, subjects' average epilepsy duration was approximately 2106 years. 85.3% and 89.1% of patients used 2-3 combined AEDs with or without vagus nerve stimulation.

The above is the content of the manual, I hope it can help you!

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.