sirolimus医保后价格

Sirolimus is a powerful immunosuppressant that not only has less nephrotoxicity, anti-proliferation, and anti-tumor effects, but can also reduce adverse reactions such as liver and kidney toxicity and serious infections in kidney transplant recipients. Kidney transplant recipients may also benefit from treatment with the drug. This drug has been approved for domestic marketing in 2000. After its launch, the price of the drug and its inclusion in medical insurance have always been a common concern of patients. Let's take a look at it together.

Normally, patients can buy a box of the small-sized medicines they need for about $500. After being reimbursed by medical insurance, patients often need to spend about $140 to purchase a box. Affected by regional medical insurance policies and other factors, there will be certain differences in the final reimbursement ratio of this drug. Patients across the country need to consult relevant departments.

Pregnant and lactating women should pay attention to:

(1) Pregnancy

①Research on sirolimus in pregnant women is still blank or limited. In animal studies, sirolimus has been associated with embryonic/fetal toxicity, manifested by stillbirth and reduced fetal weight (concomitant with delayed skeletal ossification).

②During pregnancy, this product should be used only when the potential benefits of sirolimus outweigh the potential risks to the embryo/fetus.

③Adequate and well-controlled clinical trials have not been conducted in pregnant women. Effective contraception should be used before starting treatment with sirolimus, during treatment, and for 12 weeks after stopping treatment. During pregnancy, sirolimus should be used only if the potential benefits outweigh the potential risks to the embryo/fetus.

(2) Medication during lactation

Sirolimus is excreted in trace amounts in the milk of lactating rats. It is unknown whether sirolimus is excreted in human milk. The pharmacokinetics and safety of sirolimus in infants are also unclear. Considering that many drugs are excreted in human milk and the potential adverse effects of sirolimus in nursing infants, the decision to discontinue breastfeeding or discontinue the drug should be based on the importance of the drug to the mother.