What is Vonoprazan?

Vonoprazan(Vonoprazan) is a drug called a potassium competitive acid blocker (PCAB). Vonoprazanand amoxicillin are used to eliminate Helicobacter pylori, a bacteria that causes ulcers (ulcers in the lining of the stomach or intestines). Compared to other potassium competitive acid blockers (PCABs), vonoprazan has a higher positive point charge (pKa is 9.06). This allows vonoprazan to accumulate at higher concentrations in the canalicular spaces of the gastric parietal cells, where it competes with adenosine triphosphatase in H+, K+-potassium in a competitive and reversible manner. With otherPCABs (such asSCH28080)or proton pump inhibitors(such as Lanso Compared with lazole), vonoprazan has stronger H+, K+-ATP enzyme inhibitory activity. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to help you learn more about high-quality overseas drugs.