How much does dacomitinib/dacomitinib cost approximately per month?

Dacomitinib/Dacomitinib (Dacomitinib) is a second-generation irreversible targeted drug for EGFR-mutated non-small cell lung cancer . The daily dosage is 45 mg orally once daily until disease progression or unacceptable toxicity occurs. When patients receive dacomitinib treatment, drug cost is a key concern, especially for patients on long-term treatment. A reasonable budget can help with treatment continuity and affordability.

In the domestic market, dacomitinib has been launched and included in Class B medical insurance. The common specifications are15mg*30 tablets per box. According to the daily 45 mg dosage regimen, approximately three boxes of medication are required per month. Calculated at market prices, each box costs more than 1,000 yuan, and the overall monthly drug cost may be around 3,000 to 4,000 yuan. Medical insurance coverage can appropriately reduce patients’ out-of-pocket burden, but actual expenditures still depend on the medical insurance reimbursement ratio and the procurement prices of hospitals in each region.

In addition, overseas markets also provide original drugs and generic drugs of dacomitinib. The price of overseas original drugs is usually slightly higher, but some Lao generic drugs offer more economical options. The active ingredients of generic drugs are the same as those of domestic original drugs, ensuring efficacy and safety. Their common specifications are 45mg*30 tablets per box, and the price is about RMB 800 (may be adjusted due to exchange rate fluctuations). For patients under great financial pressure, purchasing overseas generic drugs through legal and formal channels can achieve continuation of treatment while ensuring efficacy and safety.

Drug costs are only a part of the total cost of treatment. While using dacomitinib, patients also need to consider the costs of regular review, follow-up, drug side effects management and auxiliary supportive treatment. Therefore, when formulating long-term treatment plans, doctors and patients should consider drug costs, efficacy expectations, and quality of life, and rationally arrange medication cycles to maximize efficacy and affordability.

Reference materials:https://www.pfizer.com/products/product-detail/vizimpro