How much does a box of brigatinib/brigatinib cost in 2025? Latest price reference

Brigatinib/Brigatinib (Brigatinib) is an oral targeted drug for ALK-positive non-small cell lung cancer. It can be used for patients who are new to treatment or who are resistant to crizotinib. Its main mechanism of action is to irreversibly inhibit ALK kinase activity and block downstream signaling, thereby inhibiting tumor cell proliferation, inducing apoptosis and delaying disease progression. At the same time, brigatinib also shows efficacy on the central nervous system in patients with brain metastases, which makes it irreplaceable in the treatment of advanced NSCLC.

Brigatinib is currently on the market in China and has been included in the Class B medical insurance directory, providing financial support to patients. There are various specifications of medicines on the market, including 30mg 14 tablets, 90mg 7 tablets or 7 tablets 4 boards, and 180mg 7 tablets * 4 boards and other different packaging forms. Due to the high research and development costs and complex production processes of original drugs, their prices in the domestic market are relatively high, and each box may be sold for close to 10,000 yuan. For patients who need to take it for a long time, the financial burden is heavy, so it is of practical significance to know information about alternative overseas generic drugs.

The generic brigatinib drugs provided in overseas markets are basically the same as the original drugs in terms of ingredients, and the price is more cost-effective. For example, the price of a 90mg*30 tablet generic drug produced by a Lao pharmaceutical factory is about RMB 500 per box (the price may be adjusted due to exchange rate fluctuations). This generic drug is legally available and provides patients with an affordable option to continue their treatment.

Regardless of the domestic original drug or overseas generic drug, when using brigatinib, you need to strictly follow the doctor's instructions, including the initial dose, maintenance dose and monitoring indicators. When purchasing and taking medicine, patients should confirm that the source of the medicine is formal and maintain regular review and follow-up to ensure efficacy and safety. At the same time, brigatinib may cause side effects during long-term use, such as rash, diarrhea, abnormal liver function, and increased blood pressure. Timely monitoring and management can help maintain the continuity of treatment.

Reference materials:https://www.alunbrig.com/