How much does a box of Serputinib/Serpatinib cost? Price reference

Selpercatinib/Selpercatinib is an oral targeted drug specifically targeting RET gene fusions or mutations. It is a precision treatment drug developed by Eli Lilly and the first to be approved for marketing in the United States. It is used for a variety of RET-driven cancer types. It is currently one of the most representative drugs among RET signaling pathway inhibitors. With the popularity of the concept of precision medicine in the global cancer treatment field, the clinical value and market demand of seputinib continue to increase.

In terms of indications, seputinib is mainly used for four types ofRET-related tumors, such as RET fusion-positive non-small cell lung cancer (NSCLC), RET mutant thyroid The approval of this "pan-cancer" indication for adenomedullary carcinoma (MTC), RET fusion-positive thyroid cancer (TC), Others RET fusion-positive solid tumors, enables the use of seputinib across cancer types and is suitable for patients with a variety of rare or refractory tumors. Because of its precise inhibition of the RET pathway, seputinib has shown a high objective response rate in clinical practice and significantly prolonged the disease stabilization time.

In terms of price, seputinib, as an imported original targeted drug, is relatively expensive. The original drug is currently on the market in China, but has not yet been included in the national medical insurance catalog. Taking the domestic market as an example, the price of a box of seputinib with a specification of 80mg*56 capsules is expected to be more than RMB 10,000. The specific price fluctuates slightly due to regional and channel differences. In overseas markets, the European and American version of the original research version of Seputinib is priced higher, which may range from 20,000 yuan to more than 100,000 yuan in RMB, affected by factors such as exchange rates and tariffs.

Generic versions of seputinib have appeared in some overseas countries. For example, the generic version of Selpercatinib launched by a Lao pharmaceutical company has a specification of 40mg*120 capsules/box and the price is about more than 2,000 yuan. The ingredients of this type of generic drugs are basically the same as those of the original drugs, and their quality and efficacy have been medically recognized in some regions, providing patients with more economical medication options.

Reference:https://en.wikipedia.org/wiki/Selpercatinib