Market price analysis of Everolimus single box

Everolimus (Everolimus) is a multi-purpose targeted drug with outstanding advantages in the fields of anti-cancer, immune regulation and rare disease treatment. It precisely inhibits the mTOR signaling pathway and blocks the proliferation and angiogenesis of tumor cells, thereby achieving the therapeutic purpose of "inhibiting growth". Compared with traditional chemotherapy, the biggest advantage of everolimus is that its mechanism of action is more precise and does not kill normal cells in a large area. Therefore, it is more tolerable and its side effects are relatively controllable. Clinically, everolimus has been widely used in advanced renal cell carcinoma, hormone receptor-positive breast cancer, pancreatic neuroendocrine tumors, and benign tumors caused by tuberous sclerosis, becoming an important choice in multi-line treatment.

In terms of price, the original drug of everolimus "Afinitor" has been approved for marketing in China and has been included in the medical insurance catalog. At present, the common specifications in China are 2.5 mg × 30 tablets and 5 mg × 30 tablets. The price per box is about RMB 3,000. After being included in medical insurance, the patient's out-of-pocket payment ratio will be significantly reduced. For patients who need to take long-term medication, this policy greatly reduces the financial burden. In overseas markets, everolimus generic drugs have long been on the market, and versions produced in India, Bangladesh, Laos and other countries have been circulated. Its main ingredients are the same as the original drug, and its efficacy is stable but its price is more advantageous.

For example, the Lao version of Lucius (Lucius) is about RMB 890 for 5 mg Due to the mature production process of generic drugs, equivalent efficacy and low cost, more and more patients will choose overseas generic drugs as a source of auxiliary medication. It is worth noting that overseas purchases of drugs should be through formal channels to ensure the safety and quality of the drugs.

Reference materials:https://www.drugs.com/everolimus.html