Cabozantinib price situation in 2025

As a multi-target tyrosine kinase inhibitor, cabozantinib's biggest advantage is that it simultaneously inhibits multiple signaling pathways such as VEGFR, MET, and AXL. This means that it can not only directly inhibit tumor cell proliferation, but also interfere with tumor angiogenesis and the tumor microenvironment, thereby reducing the possibility of tumor growth and metastasis. For patients with advanced renal cell carcinoma (RCC), thyroid cancer, and non-small cell lung cancer, cabozantinib provides a new option after traditional treatment options have failed. The multi-target effect gives it certain advantages in delaying disease progression, improving symptoms and maintaining quality of life, especially when tumors become drug-resistant or the need for multi-target treatment increases.

In terms of price, the original drug cabozantinib has not yet been launched in China, so domestic patients’ access to the original drug is still limited. Cabozantinib tablets currently sold in the Hong Kong market come in a variety of specifications, such as 20 mg × 30 tablets, 40 mg × 30 tablets, and 60 mg × 30 tablets. Each box sells for approximately RMB 50,000. Other overseas markets, such as Japan, Turkey and Europe, offer tablet and capsule preparation options. Tablets are priced at approximately RMB 30,000 per box and capsules at approximately RMB 40,000 per box. Prices are significantly affected by exchange rate fluctuations. Such costs are higher for patients with long-term treatment, especially in areas without medical insurance support.

In order to alleviate economic pressure, some generic versions of drugs are also available in overseas markets, and their ingredients are basically the same as the original drugs. For example, versions in Laos, Bangladesh, and India are all on the market. For example, the 20 mg × 90 tablets produced by Laos United Pharmaceuticals sell for less than 1,000 yuan per box, providing a viable option for patients with limited financial conditions. Generic drugs are consistent with the original drugs in terms of ingredients and efficacy, but there are differences in packaging and supervision. Therefore, when purchasing, you need to ensure that the channels are formal to ensure the safety and effectiveness of the drugs.

Reference:https://en.wikipedia.org/wiki/Cabozantinib