The longest time that talquetamab-tgvs can be taken and its safety

Talquetamab is a bispecific T cell-binding antibody against multiple myeloma that can activate T cells to eliminate tumor cells by binding to the CD3 receptor of T cells and the GPRC5D receptor on the surface of multiple myeloma cells. As an immunotherapy drug, the duration of use and safety of Taquinutumab are the two most concerning aspects during the treatment process.

The duration of treatment with Tacquitumab depends on the patient's disease response and physician recommendations. The drug is usually used long-term, and patients require periodic evaluation during treatment. Clinical studies have shown that taquitumumab can be used long-term in some patients with significant results. However, suitability for long-term use depends on patient tolerance and side effect profile. If a patient experiences serious side effects, the doctor may adjust the treatment plan or interrupt the medication based on the patient's specific condition.

The safety profile of tasitumumab has been favorable in clinical use, particularly in patients with myeloma. Common side effects include rash, fever, chills and other immune-related reactions. Although these side effects are usually mild, more severe immune reactions, such as cytokine release syndrome (CRS), may occur in some patients. Therefore, doctors will closely monitor the patient's immune response and take appropriate treatment measures when using Taquitutumab. If serious adverse reactions occur, treatment may need to be suspended or adjusted.

In addition, due to the immunomodulatory effect of Taquitumab, patients may be at increased risk of infection during treatment. Therefore, it is necessary to regularly evaluate whether it is appropriate to continue taking the drug based on the patient's immune function. In general, the treatment duration of taquitumab is relatively flexible and can be adjusted based on the patient's specific response. Patients should maintain close communication with their doctors to ensure the safety and effectiveness of treatment.

Reference materials:https://www.talveyhcp.com/