What are the methods of using ibrutinib/Eco and what are the specific steps?

Ibrutinib/Ibrutinib (Ibrutinib) is a targeted therapy drug that is a Bruton's tyrosine kinase (BTK) inhibitor and is used to treat various types of lymphatic system diseases, including mantle cell lymphoma (M CL), marginal zone lymphoma (MZL), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL) and Waldenström macroglobulinemia (WM), etc.

The dosage and administration of ibrutinib will vary based on the type of disease and age of the patient. Typically, ibrutinib is taken orally once daily. The specific usage is as follows:

1. Treatment of mantle cell lymphoma (MCL) and marginal zone lymphoma (MZL): For adult patients with mantle cell lymphoma and marginal zone lymphoma, the recommended dose is 560 mg orally once daily. This dosage is suitable for most adult patients, and patients should take the medication at the same time each day to help keep drug levels in the body stable.

2. Chronic lymphocytic leukemia/Small lymphocytic lymphoma (CLL/SLL): For patients with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL), the recommended dose is 420 mg orally once daily. This dose helps to effectively control the condition, and patients typically maintain this dose over long-term use.

3. Waldenström macroglobulinemia (WM): Ibrutinib is also commonly used to treat Waldenström macroglobulinemia. The recommended dose is 420 mg once daily. Patients should follow the doctor's instructions and take medication strictly on time to ensure the therapeutic effect.

4. Chronic graft-versus-host disease (cGVHD): For patients 12 years of age and older, the dose of ibrutinib is 420 mg orally once daily. For pediatric patients 1 to 12 years of age, the dose is 240 mg/m², with a maximum dose of 420 mg daily. When using ibrutinib to treat chronic graft-versus-host disease, the dose and duration of treatment should be adjusted based on the patient's weight and clinical response.

Reference materials:https://www.imbruvica.com/