Differences in price and efficacy between the generic version of Valganciclovir and the original drug

The original drug of Valganciclovir (Valganciclovir) is widely used in clinical practice for the treatment of cytomegalovirus (CMV) infection and post-transplantation prevention. The price of the original research drug 0.45g*60 tablets on the domestic market is about 14,000 to 5,000 yuan. Since it has not yet been included in medical insurance, patients are under great pressure to pay out of pocket. Overseas original drugs include imported versions from Switzerland, Indian versions and Turkish versions, with prices usually ranging from more than 4,000 to 15,000 yuan. The difference is mainly affected by the place of origin, supply chain and drug specifications. Original drugs have undergone rigorous clinical verification in terms of efficacy and safety and are the standard treatment option.

In terms of generic drugs, the generic version of Vancevi produced by Lucius in Laos has been officially launched, with a price of more than 1,000 yuan, which is significantly lower than the cost of the original drug. Although the price is low, the officially marketed generic drugs are basically the same as the original drugs in active ingredients and chemical structure, so the theoretical efficacy should be similar to the original drugs. For patients with limited financial conditions or high long-term medication needs, generic drugs provide a viable alternative while reducing the economic burden.

In clinical practice, the difference in efficacy between original drugs and regular generic drugs is usually not significant, but attention needs to be paid to drug sources and quality supervision. Original drugs are fully supported by clinical research, and doctors and patients are more experienced in efficacy, safety, and drug interactions. Although generic drugs are effective, it is still recommended to observe the patient's blood count, renal function, and changes in CMV viral load under the guidance of a doctor in the early stages of use to ensure that the efficacy is up to standard. It is not recommended to use informal generic drugs that have not been formally approved to avoid unstable drug efficacy or safety risks.

Taken together, original drugs are suitable for patients who seek stable efficacy and experienced doctors, while regular generic drugs have advantages in terms of cost and accessibility, and are especially suitable for patients with long-term maintenance treatment or patients with greater financial pressure. No matter which version you choose, you need to use it strictly in accordance with the doctor's instructions, and regularly monitor blood and kidney function to ensure efficacy and safety, and avoid changing the source or dosage of the drug on your own.

Reference materials:https://www.drugs.com/