What are the medical insurance reimbursement conditions for Bedaquiline?

Bedaquiline tablets (Bedaquiline)’s reimbursement conditions are limited to multi-drug-resistant tuberculosis patients. Bedaquiline tablets have been marketed in China and have been included in Class B medical insurance. Patients can You can buy it, but the price is very high. The price of 100mg*24 tablets is around 15,000 yuan. Please consult the local hospital pharmacy for specific prices. There are only original drugs abroad, and the more cost-effective ones are Russian original drugs. The price of 100mg*188 tablets is also about 15,000 yuan. The specifications are about 8 times that of domestic ones. Relatively speaking, the price is still very cheap compared to domestic ones. And the ingredients of domestic and foreign original drugs are consistent.

Bedaquiline tablets are mainly used to treat pulmonary tuberculosis, especially multidrug-resistant tuberculosis (MDR-TB). Multidrug-resistant tuberculosis refers to tuberculosis caused by tuberculosis bacteria that are resistant to conventional anti-tuberculosis drugs such as isoniazid and rifampicin. Bedaquiline tablets are often used in combination with other anti-tuberculosis drugs as part of a comprehensive treatment regimen to improve treatment effectiveness and success rate.

Bedaquiline tablets work by inhibitingATPsynthase during the cell wall synthesis of Mycobacterium tuberculosis. ATPSynthase is an important enzyme in bacterial cells and participates in the process of energy metabolism. Bedaquiline tablets bind to the ATP subunit c synthase in the bacterial cell wall, blocking the normal function of the enzyme, causing the bacteria to be unable to carry out normal energy metabolism and growth and replication, thereby producing a bactericidal effect on Mycobacterium tuberculosis.