What is Brigatinib?

Brigatinib/Brigatinib (Brigatinib) is an oral anti-tumor drug that is a tyrosine kinase inhibitor (tyrosine kinase inhibitor). It is mainly used to treat certain types of non-small cell lung cancer (NSCLC), especially ALK fusion-positive NSCLC.

Brigatinib/The mechanism of action of Brigatinib is through inhibiting ALK (anaplastic lymphoma kinase) and ROS1 (c-ros oncogene 1) The activity of these two proteins blocks the abnormal activation of cell signaling pathways and reduces the growth and spread of tumor cells. ALK and ROS1 are tyrosine kinases that are mutated or fused in some NSCLC patients, promoting tumor formation and progression. Brigatinib/The inhibitory effect of Brigatinib can block these abnormal signaling pathways and inhibit the proliferation of tumor cells.

Brigatinib/Brigatinibis administered orally and is available in tablet form. It is generally recommended to take it after meals and to take it exactly as directed by your doctor and dosage.

Brigatinib/Brigatinibis an important option for the treatment of ALKpositive NSCLC in select patient populations. It has been approved for first-line and second-line treatment and is also useful in patients who have received treatment with other ALK inhibitors and developed resistance.

Brigatinib/Brigatinib has been launched in China and has been included in medical insurance. Since it has just been approved for marketing, patients may not be able to buy it in domestic pharmacies. If you need to purchase it in China, please consult the local pharmacy. However, the price is quite high, more than 10,000 yuan. Foreign Brigatinib/Brigatinib are mainly generic drugs, mainly Bangladeshi and Laos generic drugs. The price of the international version of the Bangladeshi generic drug Yaopin is about 2000yuan, the specification is 90mg*30 tablets; the price of the Laos version of the generic drug is about 600, and the specification is smaller. And the ingredients of domestic original drugs and foreign generic drugs are basically the same.