How much does Cabozantinib cost?

Cabozantinib (Cabozantinib) is an oral targeted anti-cancer drug mainly used to treat various types of cancer. It is a multi-target tyrosine kinase inhibitor that acts on multiple signaling pathways to inhibit tumor growth and spread.

Cabozantinib was originally approved to treat adults with medullary thyroid cancer (medullary thyroid cancer), a rare subtype of thyroid cancer. In addition, it is approved to treat cancers such as renal cell carcinoma (renal cell carcinoma) and hepatocellular carcinoma (hepatocellular carcinoma).

Cabozantinib is not currently on the market in China and is therefore not included in medical insurance because it requires approval from the National Medical Products Administration. Therefore, patients cannot purchase it domestically and need to purchase it through overseas channels. There are original and generic cabozantinib drugs abroad. The original drugs are mainly Japanese original drugs, Turkish original drugs and European original drugs. The price is relatively high, ranging from 35,000 to 46,000 yuan. Foreign generic drugs are mainly Lao generic drugs and Bangladeshi generic drugs, with prices ranging from 1,300 to 2,700 yuan. The price is much cheaper than original drugs and is more suitable for the needs of patients in ordinary families. The ingredients of original drugs and generic drugs are basically the same.

The main mechanism of action of this drug includes inhibiting vascular endothelial growth factor receptors (VEGFR), epinephrine/norepinephrine receptors (RET), tumor microenvironment receptors (MET), etc. These receptors play important roles in tumor growth, neovascularization, and metastasis, so by inhibiting these receptors, cabozantinib can slow tumor growth and metastasis.

However, like all medications, cabozantinib has some side effects that may vary from person to person. Common side effects include fatigue, diarrhea, high blood pressure, hand-foot syndrome (redness, swelling, pain in the hands and feet), mouth ulcers, etc. Therefore, it is important to follow your doctor's advice when using cabozantinib or other anticancer drugs and pay close attention to any adverse reactions.