How to take Sunitinib

For patients with gastrointestinal stromal tumors (GIST) and advanced renal cell carcinoma (RCC), the recommended dose of sunitinib (Sunitinib) is < /span> 50 mg, taken orally once a day, for a course of 4 weeks, and then stopped for 2 weeks (course 4/2). For adjuvant treatment of renal cell carcinoma (RCC), the recommended dose of sunitinib is 50 mg, taken orally once a day, for a course of 4 weeks, then stopped for 2 weeks (course 4/2), for a total of 9 6-week cycles. For patients with advanced pancreatic neuroendocrine tumors (pNET), the recommended dose of sunitinib is 37.5 mg orally once daily.

In order to control the adverse reactions of sunitinib,The first dose of patients with GIST and RCC is reduced to 37.5 mg, once a day, and the second dose is reduced to once a day, 25 mg each time. For patients with pNET, the first dose is reduced to 25 mg, once a day. If the drug is not tolerated, the drug will be discontinued. Hemodialysis patients with end-stage renal disease usually do not need to adjust the initial dose, but the exposure is reduced compared with patients with normal renal function. Based on safety and tolerability, subsequent doses can be gradually increased to 2 times.

The original sunitinib drug has been launched in China and has entered the scope of Class B medical insurance. SpecificationsThe price of 12.5mg*28 tablets is around RMB 3,500. The original sunitinib drug has also been launched overseas. The price of 12.5mg*7 tablets is around RMB 1,500 (the price may fluctuate due to the exchange rate). There are also generic drugs produced in other countries. The price of 12.5mg*28 tablets produced by an Indian pharmaceutical factory is around RMB 750 (the price may fluctuate due to the exchange rate). The generic drugs produced abroad are basically the same as the original drugs at home and abroad. There may be differences in the prices of different specifications of drugs.