Which generic version of cabozantinib is better?

Cabozantinib (Cabozantinib) is an oral targeted therapy drug that is a multi-target tyrosine kinase inhibitor. It was developed by Exelixis, Inc. to treat certain cancers, especially renal cell carcinoma (kidney cancer) and thyroid cancer.

Cabozantinib is not currently on the market in China, and therefore is not included in medical insurance. Therefore, patients cannot purchase it domestically and need to purchase it through overseas channels. There are original and generic drugs of cabozantinib abroad. The original drugs are mainly Japanese original drugs, Turkish original drugs and European version of original drugs. Foreign generic drugs are mainly Lao generic drugs and Bangladeshi generic drugs, with prices ranging from 1,300 to 2,700 yuan, and the ingredients of original drugs and generic drugs are basically the same. Regularly marketed generic drugs have the same ingredients as the original drugs, but differ in price.

Cabozantinib is a multi-target inhibitor that interferes with the proliferation, angiogenesis and metastasis of tumor cells by inhibiting the activity of multiple receptor kinases. It mainly targets key receptor kinases such as vascular endothelial growth factor receptor (VEGFR), hepatocyte growth factor receptor (MET), platelet-derived growth factor receptor (PDGFR).

Cabozantinib acts on multiple key receptor kinases and inhibits the proliferation, angiogenesis and metastasis of cancer cells by interfering with their signaling pathways, thereby inhibiting the growth and spread of tumors.

Cabozantinib may cause a series of side effects, including but not limited to high blood pressure, diarrhea, fatigue, hand-foot syndrome, skin inflammation, etc. Therefore, patients should pay close attention to their physical condition and follow their physician's monitoring and recommendations while using cabozantinib.

When treated with cabozantinib, patients should follow the doctor's instructions and receive regular medical monitoring and follow-up to ensure the safety and effectiveness of the treatment. At the same time, if any new discomfort or side effects occur, please report it to your doctor promptly.