When will Cabotegravir be available in China?

Cabotegravir (Cabotegravir) is a new type of antiretroviral drug that belongs to the category of integrase inhibitors. It is characterized by being used to treat human immunodeficiency virus (HIV) infection, especially to prevent the spread of HIV.

1.Treatment of HIVinfection: Cabotegravir is an integrase inhibitor that inhibits the integrase activity of HIV virus, preventing the virus from transcribing its RNA into the host cell's DNA and integrating it into the host cell's genome. In this way, it can effectively inhibit the replication and reproduction of HIV virus, thereby reducing the amount of virus in the host body.

2.Long-acting injection to prevent HIV transmission: In addition to being used to treat HIV infection, cabotegravir has also been studied to prevent HIV transmission. Especially in the form of long-acting injections, this treatment is called long-acting preventive antiretroviral therapy (Long-Acting Pre-exposure Prophylaxis, LAPR) or long-acting preventive therapy (Long-Acting Pre-exposure Chemoprophylaxis, LAPC). Long-acting injection of cabotegravir can be continuously released in the body, providing sustained antiviral effects and reducing the risk of HIV infection in high-risk groups.

3.Treatment options: Cabotegravir is usually used as part of combined antiretroviral therapy (Combined Antiretroviral Therapy, cART). Combination therapy uses two or more different types of antiretroviral drugs at the same time to slow down the replication of HIV viruses, reduce viral load, improve immune function, delay the progression of HIV disease, and at the same time reduceHIVRisk of transmission.

Cabotegravir is not currently on the market in China, so patients cannot purchase it domestically and need to purchase cabotegravir through overseas channels. Foreign cabotegravir only has original drugs, mainly European original drugs, and the price is very high, about 16,000 yuan.