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Cabotegravir (Cabotegravir) is a new type of antiretroviral drug that belongs to the category of integrase inhibitors. Its mechanism of action is by inhibiting the integrase activity of human immunodeficiency virus (HIV), thereby preventing the virus from transcribing its RNA into the host cell's DNA and integrating it into the host cell's genome. In this way, it can effectively inhibit the replication and reproduction of HIV virus, thereby reducing the amount of virus in the host body.

Cabotegravir was originally developed as an oral drug to treatHIV infection. However, in recent years, it has also been studied for long-term prevention of HIV transmission. Especially in the form of long-acting injections, this treatment is called long-acting preventive antiretroviral therapy (Long-Acting Pre-exposure Prophylaxis, LAPR) or long-acting preventive therapy (Long-Acting Pre-exposure Chemoprophylaxis, LAPC). Long-acting injection of cabotegravir can be continuously released in the body, providing sustained antiviral effects and reducing the risk of HIV infection in high-risk groups.

It is important to note that cabotegravir is a prescription drug and must be used under the supervision of a physician. For patients treated for HIV infection, cabotegravir is often given as part of combination antiretroviral therapy (cART) to provide more effective treatment. For patients who are using cabotegravir to prevent HIV transmission, they need to strictly follow the doctor's recommendations and treatment plan to ensure the effectiveness of long-term prevention.

As with any drug, cabotegravir may also cause some side effects. Therefore, patients should follow their doctor's advice when using cabotegravir, conduct regular follow-up and evaluation, and promptly report any adverse reactions or problems. Only by using drugs correctly under the guidance of a doctor can you achieve the best therapeutic effect and reduce the risk of adverse reactions.

Cabotegravir is not currently on the market in China, so patients cannot purchase it domestically and need to purchase cabotegravir through overseas channels. Foreign cabotegravir only has original drugs, mainly European original drugs, and the price is very high, about 16,000 yuan.