How to use Sonidegib

Sonidegib is indicated for adult patients with locally advanced basal cell carcinoma (BCC) who have recurred after surgery or radiotherapy, or who are not suitable for surgery or radiotherapy. Patients should verify pregnancy status in females of reproductive potential before initiating treatment with this drug, and serum creatine kinase (CK) levels and renal function testing should be obtained in all patients. The recommended dose of solidegib is200mg, taken orally once a day on an empty stomach, at least 1 hour before or 2 hours after a meal.

For patients with severe or intolerable musculoskeletal adverse reactions, first-time serum CK elevation between 2.5 and 10 times the upper limit of normal (ULN), and recurrent serum CK elevation between 2.5 and 5 times ULN, the dose of Solidagib should be interrupted, and after the clinical signs and symptoms disappear, solidagib should be resumed at 200 mg per day. For patients whose serum CK elevation exceeds 2.5 times the ULN and whose renal function worsens, who have a serum CK elevation greater than 10 times the ULN, who have recurrent serum CK elevation greater than 5 times the ULN, or who have recurrent severe or intolerable musculoskeletal adverse reactions, Solidegib should be permanently discontinued.

Solidagen is a new type of drug for treating diseases. Although the original drug Solidagen has been marketed in China, it has not yet entered the scope of medical insurance, and its price has not yet been determined. The Original drug Solidaget listed overseas, European version specificationsThe price per box of 200mg*30 tablets is around RMB 46,000 (the price may fluctuate due to the exchange rate), which is relatively expensive. The ingredients of the two drugs are basically the same. There is currently no generic version of Solidaget produced and marketed. For specific prices and drug information, please consult Yaodei Medical Consultants.