Will taking Sonidegib for three months be effective?

Sonidegib is a Hedgehog signaling pathway inhibitor approved for patients with advanced basal cell carcinoma (BCC) who are not suitable for surgery or radiotherapy. Solidegibis a transmembrane protein involved in Hedgehog signal transduction and plays a key role in stem cell maintenance and tissue repair. Solidegib is administered orally as an opaque pink capsule. The recommended dose is 200 mg once daily on an empty stomach, at least 1 hour before or 2 hours after a meal, until disease progression or unacceptable toxicity occurs. Before starting treatment with solidegib, make sure the patient is not pregnant.

Two patients with relapsed and refractory tumors were treated with 200 mg/day of solididegib. Two patients with locally advanced basal cell carcinoma went into remission within 7 months, and the patient with Gorlin syndrome experienced a reduction in the size and number of lesions after 4 months. Adverse reactions reported by these patients included cramping, alopecia, aging, and weight loss, all of which were mild and consistent with the known toxicity profile of Sonoge. Solidegib plays an important role in the effective treatment of advanced basal cell carcinoma.

Solidagen is a new type of drug for treating diseases. Although the original drug Solidagen has been marketed in China, it has not yet entered the scope of medical insurance, and its price has not yet been determined. The Original drug Solidaget listed overseas, European version specificationsThe price per box of 200mg*30 tablets is around RMB 46,000 (the price may fluctuate due to the exchange rate), which is relatively expensive. The ingredients of the two drugs are basically the same. There is currently no generic version of Solidaget produced and marketed. For specific prices and drug information, please consult Yaodei Medical Consultants.