Is darunavir included in medical insurance? How much is the reimbursement?

Darunavir (Darunavir) is a drug used to treat human immunodeficiency virus (HIV) infection. It belongs to the HIV protease inhibitor category and is widely used in antiretroviral therapy (ART) to help control viral replication, maintain immune system function, reduce viral load, and slow down the progression of HIV infection. Here are more details about darunavir:

Darunavir is currently on the market in China, but it has not yet been included in medical insurance. Patients can buy it at domestic pharmacies at a price of around 2,000 yuan. Please consult the local hospital pharmacy for details. The cheaper ones abroad are Indian generic drugs, which cost around 320 yuan, and the ingredients of original drugs and generic drugs are basically the same.

Darunavir prevents the virus from replicating and propagating in host cells by inhibiting the protease activity ofHIV virus. It binds to the HIV protease and blocks the cleavage and assembly of viral proteins, thereby preventing the formation of new viral particles.

Darunavir is used to treatHIV infection, usually as part of ART. It is indicated for patients with known or suspected resistance to other antiretroviral drugs, as well as for patients who are treatment-naïve or need to change treatment. Darunavir is rapidly absorbed after oral administration and reaches its highest concentration. Often used together with Ritonavir (Ritonavir), Ritonavir can enhance the drug concentration of darunavir, thereby improving its efficacy.

The dosage and usage vary according to the specific conditions of the patient and must be used under the guidance of a doctor. It is usually recommended to take it orally, with meals. Darunavir may cause some side effects, including but not limited to: nausea, vomiting, diarrhea, headache, skin reactions, liver function abnormalities, lipid metabolism disorders, etc. The severity of side effects varies between individuals.