Is Dolutegravir Sodium a blocking drug?

Dolutegravir Sodium is a drug, but it is not a blocker (anti-blocker). It belongs to a class of antiretroviral drugs called Integrase Strand Transfer Inhibitors (INSTIs).

Dolutegravir sodium is mainly used to treat human immunodeficiency virus (HIV) infection. It prevents the virus from integrating its own genetic material into the host genome within the host cell by inhibiting the enzyme activity of HIVreverse transcriptase. In this way, it can effectively block the replication and spread of HIV, thereby reducing the viral load, slowing the progression of the disease, improving the patient's immune status, and prolonging the patient's life.

However, it should be noted that dolutegravir sodium is usually used in combination therapy with multiple antiretroviral drugs (combination antiretroviral therapy, ART) rather than as a standalone treatment. The combined use of ART is designed to reduce viral replication and slow the progression of HIV infection, improving patients’ quality of life. Treatment plans need to be personalized based on the patient's specific situation and the virus's resistance. Please use any medicine under the guidance of a professional doctor.

Dolutegravir sodium has been launched in China, but it has not yet been included in medical insurance. Patients can buy it in hospital pharmacies, and the price is around 1,200 yuan. Please consult the local hospital pharmacy for specific prices. Dolutegravir sodium is cheaper abroad, mainly Indian generic drugs, with a price of around 350 yuan, and the ingredients of domestic original drugs and foreign generic drugs are basically the same.