Entrectinib medical insurance price in 2023

Entrectinib (Entrectinib) belongs to the class of multi-target tyrosine kinase inhibitors (TKI). Its main function is to inhibit abnormal signaling caused by specific gene mutations in cancer cells, thereby inhibiting the growth and spread of tumor cells.

Entrectinib has been launched in China, but due to its short time on the market, it has not yet been included in the medical insurance catalog. Since it has just been launched, it is difficult to purchase domestically and the price is very high. For specific prices, please consult the hospital pharmacy at that time. There are original drugs and generic drugs abroad. The original drugs abroad are mainly European versions of original drugs. The price is about 45,000 yuan. The price is relatively high and may be unaffordable for ordinary families. Generic drugs are mainly Lao generic drugs, with prices ranging from 4,000 to 8,000yuan, which are much cheaper than original drugs, and the ingredients of original drugs and generic drugs are basically the same.

Entrectinib not only acts on a single molecular target, but can also inhibit multiple targets simultaneously. This allows it to show a better inhibitory effect on tumor cells carrying multiple gene mutations. The efficacy of entrectinib is closely related to whether the patient carries a specific gene mutation. Genetic testing is often required before use to determine whether a patient is a candidate for treatment with the drug. This personalized treatment strategy helps improve treatment effectiveness and reduce unnecessary side effects.

Entrectinib not only shows significant efficacy in specific types of tumors, but also shows potential therapeutic activity in many different types of tumors. This makes it a versatile targeted agent that can provide treatment options for a variety of patients. Due to its multi-target effect, entrectinib has a lower risk of drug resistance than first- or second-generation targeted drugs. This helps prolong the patient's response to the drug and improves the continuation of treatment.