Who is the Indian version of Trifluridine (Lonsurf) manufacturer?

Trifluridine (Lonsurf), a common drug, is a combination drug used to treat adult patients with metastatic colorectal cancer (HCC) and metastatic stomach or gastroesophageal junction adenocarcinoma. TrifluridineThe Indian version of tipiracil tablets is manufactured by IndiaNatco Pharmaceuticals. Its drug ingredients are basically the same as those of the original drug, but there is a difference in price. The price of 15mg*20 tablets may be around RMB 1,000 (the price may fluctuate due to exchange rates).

Patients treated with trifluridine tipiracil had previously received fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy (an anti-VEGF biologic therapy) and RAS wild-type (an anti-EGFR therapy). TrifluridineA single agent can be used to treat primary keratoconjunctivitis and recurrent epithelial keratitis caused by herpes simplex virus. After oral administration of this drug, at least 57% of the trifluridine content is absorbed, and in patients with advanced solid tumors, the average time to reach peak plasma concentration is approximately 2 hours.

Trifluridine tipiracil tablets are sold under the trade name ofLonsurf. The original drug is already on the market in China. The price of 20mg*20 tablets may be around RMB 7,000. Due to its short time on the market, it has not been covered by medical insurance. The price of the Hong Kong versionTrifluridine Tipiracil Tablets Specification20mg*20 tablets may be around RMB 13,200, and the Japanese versionTrifluridine Tipiracil Tablets Specification20mg*20 tablets may be priced around RMB 5,700 (the price may fluctuate due to exchange rates).