Is there an Indian version of Pirfenidone?

Pirfenidone (Pirfenidone) has an Indian version, which belongs to the production category of generic drugs. Its pharmaceutical ingredients are basically the same as those of the original drug Pirfenidone, and is used to treat idiopathic pulmonary fibrosis (IPF). The price of each box of 200mg*30 tablets is around RMB 100 (the price may fluctuate due to the exchange rate). The drug must be purchased through formal channels.

Pirfenidone has well-established anti-fibrotic and anti-inflammatory properties in various in vitro systems and animal models of fibrosis. Many cell-based studies have shown that pirfenidone reduces fibroblast proliferation, inhibits transforming growth factor β-stimulated collagen production, and reduces the production of fibrogenic mediators such as transforming growth factor β. Pirfenidone has also been shown to reduce the production of inflammatory mediators (such as tumor necrosis factor alpha and IL-1β) in cultured cells and isolated human peripheral blood mononuclear cells. These activities are consistent with the broader anti-fibrotic and anti-inflammatory activities observed in animal models of fibrosis. Pirfenidone is administered orally. Although the presence of food can significantly reduce the extent of absorption, the drug should be taken after meals to reduce drug-related nausea and dizziness. The drug is approximately 60% bound to plasma proteins, especially albumin.

Pirfenidone has been approved for marketing in China under the trade name of Asri. It has entered the scope of Class B medical insurance and is limited to patients with idiopathic pulmonary fibrosis. The specifications produced by domestic pharmaceutical factoriesThe price of 100mg*54 tablets per box is around RMB 500. For more drug information and specific prices, please consult Yaodei Medical Consultant.