How effective is domestically produced Pirfenidone?

The pharmaceutical ingredients of domestically produced pirfenidone (Pirfenidone) are basically the same as those of the original drug of pirfenidone, but the price is different due to different manufacturers. The trade name is Asri has entered the scope of Class B medical insurance, which is limited to patients with idiopathic pulmonary fibrosis. The price of 100mg*54 capsules produced by Beijing Contini Pharmaceutical Factory is about 500 yuan per box. This drug may be sold in domestic pharmacies or hospitals.

Idiopathic pulmonary fibrosis (IPF) is an idiopathic interstitial pneumonia; it is characterized by a gradual decline in lung function, leading to respiratory failure and death. The median survival period after initial diagnosis is about 2-5 years. Pirfenidone reduces forced vital capacity (FVC), Efficacy in reducing 6-minute walk test distance (6-MWT) and increasing progression-free survival 12 months after dosing has been demonstrated in the phase III volumetric/ASCEND population and in cohorts from Belgium and the Netherlands. Long-term data on disease progression in patients with idiopathic pulmonary fibrosis treated with pirfenidone remain limited. More than half of the patients who took pirfenidone survived, compared with one-third of those who didn't take the antifibrotic drug.

There are also generic pirfenidone drugs produced in other countries overseas, such as the specifications produced by Indian pharmaceutical factoriesThe price of each box of 200mg*30 tablets is around RMB 100 (the price may fluctuate due to the exchange rate). The ingredients of the generic drugs are basically the same as those of the original drugs. For more drug information and specific prices, please consult Yaode Medical Consultant.