What Finerenone does

Finerenone (Finerenone) is a ketosterol receptor antagonist mainly used to treat cardiovascular disease and diabetes-related kidney disease. Its mechanism of action mainly involves the antagonism of aldosterone receptors, resulting in the following important effects:

1. Inhibiting aldosterone receptors: Aldosterone is a hormone that regulates salt and water balance and the maintenance of blood pressure in the body. However, in certain disease states, such as heart failure, diabetes, etc., aldosterone may be overactive, causing an imbalance in the body. Fennelidone reduces the impact of aldosterone on the cardiovascular system and kidneys by selectively antagonizing aldosterone receptors, thereby adjusting body fluid balance and reducing the burden on the cardiovascular system.

2. Reduced risk of heart failure recurrence: In patients with chronic heart failure (CHF), the effect of fenelidone can reduce the risk of heart failure recurrence. By antagonizing aldosterone receptors, it helps reduce the burden on the heart, improve heart function, relieve symptoms of heart failure, delay the progression of the disease, and improve the patient's quality of life.

3. Renal protection: Overactivity of aldosterone in the kidneys may lead to renal inflammation and fibrosis, thereby affecting kidney function. The antagonism of fenelinone protects the kidneys from damage and reduces the risk of developing kidney disease in patients with type 2 diabetes. By modulating inflammatory and fibrotic processes, it helps maintain normal kidney function.

4. Improved quality of life for patients: The effects of fenelidone help improve heart failure symptoms, reduce the risk of heart failure recurrence, and reduce the progression of kidney disease. These effects not only help protect cardiovascular and renal health, but also improve patients' quality of life and reduce the distress of related symptoms.

Fenelidone is currently on the market in China and has been included in medical insurance. Patients can purchase it at domestic hospital pharmacies. For specific prices and prices after medical insurance reimbursement, please consult the local hospital pharmacy. Overseas, the main Japanese original drug is fenelidone, with a specification of 10mg*100 tablets of about more than 2,000 yuan, and it is the same as the domestic original drug.