Can I have a baby while taking Pomalidomide?

Pomalidomide is a thalidomide analogue that is teratogenic in rats and rabbits when administered during organogenesis. If a patient becomes pregnant while taking this drug, it may cause harm to the fetus. Men who take pomalidomide, which contains Pomalidomide in their semen, must always use latex or synthetic condoms during any sexual contact with a woman of reproductive potential while taking pomalidomide and for 4 weeks after stopping, even if they have had a successful vasectomy.

Pomalidomide is an analogue of thalidomide, a human teratogen that can induce a high frequency of severe and life-threatening birth defects such as Amelia syndrome(limbs) absence), brachycemia (short limbs), insufficient skeletal plasticity, bone loss, external ear abnormalities (including anotia, micropinnosis, small or absent external auditory canal), facial paralysis, eye abnormalities (anophthalmia, microphthalmia) and congenital heart defects. Gastrointestinal, urinary tract, and genital malformations have also been recorded, and approximately 40% of infants have been reported to die at or shortly after birth.

Pomalidomide, independently developed in China, has been launched domestically and has now entered the scope of medical insurance. The price of domestically produced Pomalidomide may be around RMB 4,000 per box, while the Turkish version sold overseas may be priced around RMB 15,000 per box (the price may fluctuate due to exchange rates), which is relatively expensive. There are also cheaper generic drugs produced in other countries overseas. The price of each box produced by a Lao pharmaceutical factory may be around a few hundred yuan (the price may fluctuate due to the exchange rate). The ingredients of foreign generic drugs, domestically produced drugs and foreign original drugs are basically the same. For more drug information and specific prices, please consult Yaode Medical Consultant.