Will taking Pomalidomide cause high blood potassium?

The most common side effects of pomalidomide include anemia, neutropenia, fatigue, thrombocytopenia, fever, peripheral edema, peripheral neuropathy, and infections, including pneumonia. It is understood that pomalidomide does not directly cause high blood potassium. Some of these side effects may affect electrolyte levels, including blood potassium levels.

Liver failure, including fatal cases, has occurred in patients receiving pomalidomide. Elevated levels of alanine aminotransferase and bilirubin have also been observed in patients receiving pomalidomide. Patients require monthly monitoring of liver function tests and discontinuation of pomalidomide and evaluation if liver enzymes rise. After returning to baseline values, treatment at a lower dose may be considered. Patients also need to be monitored for hematologic toxicities, particularly neutropenia, with complete blood counts weekly for the first 8 weeks and monthly thereafter. Patients may require dose interruptions and/or dose modifications.

Pomalidomide, independently developed in China, has been launched domestically and has now entered the scope of medical insurance. The price of domestically produced Pomalidomide may be around RMB 4,000 per box, while the Turkish version sold overseas may be priced around RMB 15,000 per box (the price may fluctuate due to exchange rates), which is relatively expensive. There are also cheaper generic drugs produced in other countries overseas. The price of each box produced by a Lao pharmaceutical factory may be around a few hundred yuan (the price may fluctuate due to the exchange rate). The ingredients of foreign generic drugs, domestically produced drugs and foreign original drugs are basically the same. For more drug information and specific prices, please consult Yaode Medical Consultant.