Is Fulvestrant covered by medical insurance? What is the price after reimbursement?

Fulvestrant (Fulvestrant), also known as fulvestrant fumarate, is a drug widely used to treat hormone receptor-positive breast cancer. It belongs to a class of endocrine therapy drugs and is mainly used to treat tumors with estrogen receptor (ER, estrogen receptor)-positive tumors in breast cancer patients.

Fulvestrant injection has been launched in China and has been included in medical insurance. Patients can buy it domestically. The price of domestically imported original drugs is around 5,000 to 6,000 yuan, while domestic drugs are slightly cheaper. For specific prices, please consult the local hospital pharmacy or the medical insurance bureau. There is only Fulvestrant's original drug abroad. The cheaper original drugs are mainly the Turkish original drug and the Indian version of the original drug. The price is around 1,000~2,000 yuan, and the ingredients and efficacy of the original drugs at home and abroad are the same.

Fulvestrant is an estrogen receptor antagonist that works by two mechanisms. First, it binds to estrogen receptors and prevents estrogen molecules from binding to the receptors, thereby reducing estrogen signaling and inhibiting tumor growth. Secondly, fulvestrant can reduce the number of estrogen receptors by promoting the degradation of the receptors, thus reducing the cellular response to estrogen.

Fulvestrant is primarily used to treat estrogen receptor-positive, advanced or metastatic breast cancer, especially in patients who have developed resistance to other endocrine therapies.

Fulvestrant is usually administered as an intramuscular injection once a month with an initial dose of 500 mg. Typically, patients are gradually transitioned to a stable monthly dose under their doctor's supervision. The duration of treatment will be determined based on the patient's condition and clinical response.