Is the Lao version of Gilteritinib real or fake?

Gilteritinib (Gilteritinib) is mainly used to treat a specific type of leukemia, namely acute myeloid leukemia (Acute Myeloid FLT3 gene mutation subtypes in patients with Leukemia, AML).

The Laotian generic drug of Giritinib is a generic drug officially approved by the local government for marketing. The price is about four to five thousand yuan, which is relatively cheap. In terms of drug ingredients, the ingredients of domestic and foreign original gilitinib drugs are basically the same as those of generic drugs.

Giritinib is currently on the market in China, but it is not included in medical insurance. If patients need it, they can go to the hospital to buy it at their own expense, but the price is very high, about 35,000 yuan. For specific prices, please consult the local hospital pharmacy. Foreign original drugs of gilitinib are even more expensive. For example, the price of the Hong Kong version of the original drug is around 90,000 yuan, and the European version of the original drug is as high as more than 200,000 yuan, which is simply unaffordable for ordinary patients.

FLT3(FMS-Like Tyrosine Kinase 3) is a receptor tyrosine kinase that plays an important role in normal hematopoiesis. However, in some AML patients, FLT3 gene mutations can lead to abnormal activation of FLT3 receptor tyrosine kinase, promoting abnormal proliferation and differentiation of leukemia cells.

The mechanism of action of giritinib is by inhibiting the activity of FLT3 receptor tyrosine kinase, thereby blocking the growth and differentiation of leukemia cells. This makes giritinib an effective tool for the treatment of AML patients with FLT3 gene mutations.

It should be emphasized that gilitinib is a highly selective targeted therapy drug, mainly used for specific subtypes of AMLpatient. It is not suitable for all patients with leukemia, nor is it used to treat other types of tumors. Patients should determine whether giritinib is suitable for use and how to use it correctly based on their doctor's advice and specific disease conditions.