What will happen once the targeted drug Pazopanib is stopped?

Pazopanib is a type of targeted therapy called a tyrosine kinase inhibitor (TKI). These are also known as cancer growth inhibitors and are used to treat patients with kidney cancer (advanced renal cell carcinoma). It is also used to treat advanced soft tissue sarcoma (STS) in patients who have been treated for other cancers. Pazopanib interferes with the growth of cancer cells, which are eventually destroyed by the body.

Your doctor will advise you to continue taking pazopanib as long as it is effective for you. Do not stop taking pazopanib without talking to your doctor. If you have certain side effects or if your blood test results change, your doctor may tell you to stop taking pazopanib for a short period of time or to reduce your dose. Pazopanib can relieve symptoms and reduce tumor burden. After stopping the drug, symptoms may rebound, such as pain, discomfort or other tumor-related symptoms, including nausea, vomiting, fatigue, diarrhea, etc. It may have an impact on the body's metabolic function, including increases in liver enzymes. After stopping the medication, these indicators may gradually return to normal.

PazopanibThe original drug has been launched in China and has entered the scope of Class B medical insurance, but reimbursement is limited to patients who meet the indications. The price of each box may be around 3,000 yuan. The price of pazopanib original drug specifications200mg*30 tablets marketed overseas may be around 1,000 RMB per box (the price may fluctuate due to exchange rates). There are also pazopanib generic drugs produced in other countries. The price of 200mg*30 tablets produced by Bangladesh pharmaceutical factory may be around 500 yuan per box (the price may fluctuate due to the exchange rate), which is cheaper. The pharmaceutical ingredients of generic drugs are basically the same as those of domestic and foreign original drugs.